Growth Factor Concentrate (GFC) Treatment for Hair Loss

These days, hair loss is one of the most common issues that needs to be addressed right away. Thankfully, though, it can be swiftly recovered and saved using the patient's platelets without the need for specialized surgery—that is, with Growth Factor Concentrate (GFC) Therapy Treatment.

What is Growth Factor Concentrate Therapy Treatment?

GFC is a non-surgical procedure that stimulates hair growth by using your blood platelets. By injecting growth factors and improving the local blood supply, it is a perfectly safe procedure that thickens and densifies hair in thinning or damaged areas.

Many growth agents are added to blood platelets. We at La Esthetiques, use a specially constructed GFC equipment to extract them at a high concentration from the blood. Next, using specialized equipment and personnel at the treatment location, the gathered GFC is administered. Overall, the procedure is safe, non-pyrogenic, regenerates injured tissues spontaneously, and does not result in platelet loss.

In just 3–4 sessions, patients can achieve optimal results with this cutting-edge and most recent treatment for hair loss. As a result, it's regarded as the greatest technique for hair restoration.

What are the different Growth Factors associated with GFC Treatment?

Blood platelets include a variety of growth factors that aid in tissue regeneration and repair as well as stem cell migration, proliferation, and differentiation. Consequently, the role that each GFC plays in combating hair loss varies.

Platelet-derived Growth Factor (PDGF): PDGF stimulates angiogenesis and vascularization while also aiding in the growth of hair. Additionally, it aids in the proliferation and chemotaxis of fibroblasts as well as the mitogenesis of endothelium and mesenchymal stem cells.

Vascular Endothelial Growth Factor (VEGF): During the anagen phase of hair, DP cells express VEGF, which controls perifollicular angiogenesis in the hair. To facilitate the process, it also enlarges the perifollicular vessels during the anagen growth phase.

Epidermal Growth Factor (EGF): EGF increases mesenchymal and epithelial cell mitogenesis and encourages hair cell proliferation and regeneration. It also promotes angiogenesis in addition.

Insulin-like Growth Factor-1 (IGF-1): IGF-1 functions as an angiogenesis stimulant, preserves HF growth, and boosts total hair growth.

High concentrations of them are taken out of the platelets and kept in a GFC therapy kit with exact methods.

How is GFC prepared?

Step 1: Drawing blood.

Peripheral blood from the patient (between 15 and 16 ml) is drawn and divided evenly into 4 GFC tubes.

Step 2: Growth factors, or GFs, are released and platelets are activated.

This stage involves gently mixing the blood by inverting the tube six to ten times and letting it stand for about half an hour. By releasing PDGF, VEGF, EGF, and IGF-1 from the platelets and using unique platelet-activating solution, the GFC treatment aids in the activation of platelets.

Step 3: The GFC is separated.

To help with counterbalancing, all four tubes are then centrifuged for 10 minutes at 3400 rpm. Moreover, it aids in the separation of pure GPs from the RBCs, WBCs, and other blood cells that are included in them.

Step 4: Gathering GFC.

GFC and autologous growth factor concentration are collected using the tubes. GFCs are collected at the tube's cap using a syringe to aid with the collection process. The needle tip is inserted slightly under the tube cover. It permits GFC to recuperate to its fullest.

Step 5: GFC application.

GFC has been gathered and is now prepared for application. The GFC output color spectrum includes yellow, yellowish brown, orange, and reddish.

Directions for Use?

  • One patient uses each GFC therapy kit in a single sitting.

  • For optimal effects, three sessions spread over three months are advised.

  • Reduced hair loss and an increase in hair thickness and count are the expected outcomes.

  • One session can be repeated if necessary prior to the treatment taking place every four to six months, and the complete therapy can be performed annually.

Benefits of Growth Factor Concentrate Therapy

GFC Therapy is the next-generation hair loss treatment that delivers one’s growth factors at higher concentrations

  • Extremely powerful and encourages improved and natural regeneration.

  • A guaranteed increase in hair count and thickness that is statistically significant.

  • Made entirely of the candidate's blood and completely safe.

  • There is no involvement of RBCs or WBCs, reducing the likelihood of pain and inflammation.

  • Quality and convenience are assured by the process.

  • It takes fewer sessions to achieve the best results.

  • It revitalizes hair follicles and significantly lowers hair loss.

  • It increases the volume and thickness of hair.

  • It encourages hair growth and fortifies the hair grafts.

How is GFC Therapy Different from PRP

PRP is the biological product, or fraction, of autologous blood plasma that has a platelet concentration higher than the starting point. The result varies every time. The single spin or double spin methods were applied, since it was hard to remove WBCs and RBCs. The healing effect was linked to inflammation and pain following the procedure. While using this therapy for hair loss treatment, numerous obstacles were faced- It did not offer growth factors but platelets, no standardized protocols were involved, no determining quality and quantity clarity, conflicting results, and complexity of the operation.

Only large concentrations of growth factors are obtained by platelet activation, and GFC therapies are also produced from the patient's blood. As a result, there is no platelet loss and the entire process is quite simple to carry out. Furthermore, the GFC can be stored for eight hours at ambient temperature and for seven days at 4 degrees Celsius, in contrast to PRP. This leads to the best possible overall outcomes, reduced risk of discomfort, inflammation, and infection, and a shorter total operation time.

Post-treatment Instructions to Follow?

  • For a day, refrain from touching or brushing your hair or scalp.

  • Prevent perspiration brought on by strenuous physical labor and intense exercise for four days following the surgery.

  • Only use the products that the doctor has prescribed after refraining from shampooing your hair for one to two days.

  • As directed by the physician, regular use of topical treatment or drug intake is necessary.